• December 7, 2021
Davis Chosen to Give Rising Star Showcase Presentation

Davis Chosen to Give Rising Star Showcase Presentation

Maggie T. Davis, PhD, Assistant Professor of Psychiatry, has been chosen to provide a Rising Star showcase presentation on the digital annual assembly of the Society of Organic Psychiatry (SOBP) on April 30, 2021.

Davis might be one in all six researchers featured by SOBP in its Rising Star showcase, a two-hour session that focuses on early profession investigators. Every researcher will communicate for 20 minutes. The title of Davis’s presentation is “mGluR5 Availability in Persistent Ache: An in Vivo Research With [18F]FPEB Pet Research.”

Learn extra about her presentation:

Persistent ache (CP) is a major supply of each private and public well being burden, accounting for an estimated $635 billion in care-related prices annually. Of additional concern, CP is ceaselessly handled with opioid-based analgesic drugs, resulting in excessive charges of drug misuse and ceaselessly to opioid habit. Thus, identification of other pharmacological targets able to quickly lowering ache in CP with out resulting in substance misuse should be prioritized. Dr. Davis might be presenting the outcomes of a novel in vivo PET examine analyzing the position the metabotropic glutamate receptor sort 5 (mGluR5) – a possible therapy goal for power ache with low abuse-potential – in people reporting power ache and people with no ache. Outcomes counsel markedly larger frontal in vivo mGluR5 availability in people with CP relative to demographically matched no ache people. Additional, in CP mGluR5 availability was negatively related to efficiency in choose domains of cognitive functioning (consideration and dealing reminiscence). Noticed variations in mGluR5 availability counsel a attainable position for glutamate neurotransmission, and mGluR5 particularly, within the pathophysiology of CP and spotlight the necessity for additional analysis of glutamatergic therapy targets in CP.

Davis accomplished a postdoctoral fellowship within the Yale Neuroimaging Sciences Coaching Program in 2018 below the mentorship of Irina Esterlis, PhD, Affiliate Professor of Psychiatry. Her analysis pursuits middle on use of molecular neuroimaging strategies to boost understanding of the connection between suicidal habits and stress-related psychopathology.

Submitted by Christopher Gardner on February 24, 2021

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